A couple, walked into Xenith clinic with the hope of having a baby. Upon discussing the case, it was found that they had been trying for a child for more than 5 years of their married life. They had also undergone various treatments in other clinics but could not obtain the desired outcome of conceiving.
The very long wait had resulted in much anguish. They were referred to Xenith by a gynaecologist.

Medical tests and case background

The couple’s history was taken, and they underwent all fertility tests. Husband was found to have severe oligospermia (low sperm count).
The most suitable way to get pregnant if one has very low sperm count is by opting for IVF treatment.

Fertility Advice given by Xenith

Couple was discussed about various treatment options, and they chose to undergo IVF.

The IVF procedure was performed and day 3 embryos were cryopreserved. During the entire IVF cycle, her endometrium was thin. We advised her to undergo a Hysteroscopy procedure and an endometrial tissue study for TB which was negative. The hysteroscopy revealed an atypical uterine cavity which was corrected in the same procedure.

During her FET cycle, inspite of giving good hormonal medications, her endometrium didn’t develop nicely. Multiple supplements were added. After counselling the patient, decision was taken to transfer 1 blastocyst. But the cycle failed.

The pattern of her endometrium thickness was closely observed and we opted to modify the method used to prepare the endometrium. We experienced a miraculous response. The Endometrium started showing a good thickness with a healthy blood flow.

In the next cycle of embryo transfer, different method of endometrial preparation was used. Her endometrium developed nicely with good blood flow and then 2 blastocyst were transferred.

Treatment outcome

15 days later, beta-HC G test was positive; it demonstrated more than doubling after 48 hours. 1 week later, transvaginal ultrasound confirmed the presence of a twin gestational sac inside the uterine cavity followed by confirmation of cardiac activity at six weeks of gestation. Her pregnancy went uneventful and she gave birth to two healthy babies.

The couple expressed happiness that they succeeded in the journey of parenthood. They were in deep gratitude with Dr Mamta Dighe and the whole staff of Xenith for excellent support and guidance in their entire fertility journey.

The endometrium or the lining of the womb developing well is extremely crucial for a successful IVF outcome. Some women will have a suboptimal endometrial development and resistant endometrium. It is only with a good understanding of different ways of endometrial preparations that a resistant endometrium can be made ready for successful implantation.

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