Advanced Sperm Retrieval for Improved Fertility Outcomes

Male infertility can be a challenging road, but modern medicine continues to bring hope through innovative techniques like Micro-TESE (Microsurgical Testicular Sperm Extraction). This advanced surgical procedure provides new hope for men facing infertility—particularly those with little to no sperm production—to achieve fatherhood.
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Introduction to Micro-TESE
Micro-TESE is a cutting-edge surgical sperm retrieval procedure used in the treatment of male infertility, especially in cases where sperm production is extremely low or absent (a condition known as non-obstructive azoospermia). Unlike standard methods, Micro-TESE uses a high-powered surgical microscope to precisely locate areas in the testes most likely to contain sperm.
Men who may benefit from Micro-TESE include:
- Those diagnosed with non-obstructive azoospermia
- Men with genetic or hormonal causes of impaired sperm production
- Patients who’ve had unsuccessful prior sperm retrieval attempts
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What Is Micro-TESE?
Micro-TESE involves the microsurgical extraction of sperm directly from the seminiferous tubules of the testicles. Using a powerful operating microscope, the surgeon identifies the most promising areas within the testes and extracts tissue in a highly targeted manner.
How It Differs from Other Methods:
- TESE (Testicular Sperm Extraction): A blind biopsy with lower precision
- TESA (Testicular Sperm Aspiration): Uses a needle to extract tissue, often with low yield
- PESA (Percutaneous Epididymal Sperm Aspiration): Used mainly for obstructive azoospermia
Micro-TESE stands out for its precision, minimal tissue damage, and higher sperm retrieval rates.
Who Needs Micro-TESE?
Micro-TESE is particularly beneficial for:
- Men with non-obstructive azoospermia (NOA): A condition where the testicles produce little or no sperm due to testicular failure
- Patients with failed previous sperm retrievals: Those who have undergone TESE or TESA with no success
- Men with genetic conditions: Such as Klinefelter syndrome or Y-chromosome microdeletions
- Cancer survivors: Especially those who’ve undergone chemotherapy or radiation therapy
A detailed evaluation by a fertility specialist can help determine if you are an ideal candidate.
Procedure: How Micro-TESE Works
Step-by-Step Overview:
- Anesthesia: The procedure is done under general anesthesia.
- Microsurgical Access: A small incision is made in the scrotum to expose the testicle.
- Microscopic Examination: Under high magnification, the surgeon examines the seminiferous tubules for areas that appear more likely to contain sperm.
- Tissue Extraction: Small pieces of tissue are removed for analysis.
- Sperm Identification: The sample is immediately examined under a microscope by embryologists to identify sperm.
- Cryopreservation: Viable sperm can be frozen for future use in IVF/ICSI procedures.
Recovery and Aftercare:
- Most men return to light activities within 2–3 days
- Mild discomfort, swelling, and bruising are common
- Full recovery typically takes 1–2 weeks
- Pain is usually well-managed with oral medication

- Higher Sperm Retrieval Rates: Especially in NOA patients compared to conventional methods
- Minimal Damage: Reduced trauma to testicular tissue due to precise targeting
- Improved IVF/ICSI Outcomes: Retrieved sperm are often of better quality
- Single Procedure Efficiency: Often eliminates the need for multiple retrievals
- Psychological Relief: Offers hope to couples who had lost faith in fertility treatment
Risks and Considerations
While Micro-TESE is generally safe, it’s important to understand potential risks:
- Swelling, bruising, or infection
- Temporary testicular discomfort or pain
- Rare complications: Hematoma or damage to blood vessels
- Underlying cause of azoospermia
- Testicular size and hormone levels
- Surgeon’s experience and technology used
- Coordination with a skilled IVF lab
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Rushikesh Pakade19/07/2025Thank you Mamata madam. With in 6 month we got postive results. All doctor and staff are very knowledgeable and caring .Pooja & poonam madam Explains everything clearly and listens patiently. Drs are Highly professional and compassionate.One of the best doctors I’ve ever met."Trustindex verifies that the original source of the review is Google.
SHWETA DALWATE19/07/2025🌟🌟🌟🌟🌟 I had a truly wonderful experience at Xenith Advance fertility centre. From the very first visit, the doctors and staff were incredibly supportive, professional, and compassionate. Every step of my treatment was explained clearly, and I always felt listened to and cared for. The environment is welcoming and positive, which made a huge difference during what can be a very emotional and sensitive time. The team was always available to answer my questions and made sure I was comfortable and confident throughout the journey. I am deeply thankful to the entire team Mamta Dighe mam, Dr Pooja and Dr Poonam and also the Nursing staff for their dedication and personal attention. Highly recommended to anyone looking for expert care and genuine support. 💖Trustindex verifies that the original source of the review is Google.
Dr.shree Pandey19/07/2025After struggling with a miscarriage and normal reports for over 1.5 years, I was filled with anxiety and uncertainty about my pregnancy journey. But everything changed when I visited Xenith. The entire team, especially Dr. Mamta Ma'am and Dr. Pooja, have been incredibly supportive and kind throughout my treatment. Dr. Mamta gave me hope and confidence when I needed it the most. Her gentle nature and encouraging words helped me believe again. And within just 2 months of treatment, I conceived! I am so grateful to the Xenith team for their expert care and compassion. A special heartfelt thanks to Dr. Mamta and Dr. Pooja. I highly recommend Xenith to anyone going through fertility challenges – they truly make miracles happen with love and care.♥️🥹Trustindex verifies that the original source of the review is Google.
Somnath Kangone16/07/2025Senior & Experience Dr got excellent feedback from most of patient having very Good sucess RateTrustindex verifies that the original source of the review is Google.
Sareeka Bhalekar16/07/2025Choosing Xenith IVF was a turing point in our lives. After facing many challenges in our journey to become parents, we finally found hope and success here. Right from the first visit, the entire team made us feel comfortable and confident.Their honestly, clarity and constant support made the whole IVF process much easier for us to understand and go through. We're deeply grateful to Dr. Mamta Madam ,Dr Pooja madam, Dr Poonam madam and all Xenith team for helping us.Trustindex verifies that the original source of the review is Google.
Anu Mehta15/07/2025My husband and I came to Xenith after making the decision to have our second baby in our late thirties. We did not know how fertile we were but wanted to get things in order just incase we needed intervention. After some basic fertility tests, Dr. Dighe let us know that we were in good health and could try naturally for at least 3-4 months. She was completely honest and straightforward. No excessive tests or medication were prescribed. We have continued here after a successful pregnancy. The staff is very polite, and all doctors are excellent. Our questions are always answered in detail with patience and compassion. Overall, I feel that Xenith holds itself to a high bar of integrity and professionalism. I would recommend it to anyone considering pregnancy or fertility treatments.Trustindex verifies that the original source of the review is Google.
shraddha bhole15/07/2025Doctor and staff are very co-operative. Step by step guidance and examination is provided by them. Thanks for your help to us.Trustindex verifies that the original source of the review is Google.
Priya Colaco12/07/2025Dear Dr Mamta Dighe, Dr Pallavi and everyone at Xenith... I am beyond happy to share that on 14th April I gave birth to a beautiful girl. This joy first started with you and I will forever be indebted to you and all others at Xenith (KP & Wakad) for making me believe that IVF was one of the best decisions of my life. Right from the staff at the reception to all the doctors at the centre everyone treated us with a lot of love & care. Pls pass on my love to Payal and maushi.(KP) Our heartfelt gratitude towards all of you. I hope that couples really wanting to have a baby come & see u all and get to withess the joy like us. A million thanks again. Lots of love & gratitude, Priya, Shekhar & li'l Isha 💕Trustindex verifies that the original source of the review is Google.
Swapnil Sathe03/07/2025We are very grateful and truly appreciate everything you have done for us. We are pleased and satisfied with the experience. All the doctors, nurses and staff members are very supportive and have a positive attitude. Thank you everyone☺️

At Xenith IVF Center, we bring together clinical expertise, state-of-the-art technology, and a personalized approach to give you the best chance of success.
- Experienced Andrologists and Urologists: Highly skilled in microdissection techniques
- Advanced Microscopy Equipment: Allows for optimal visualization and sperm detection
- Integrated IVF Lab: Ensures seamless coordination for sperm analysis and use
- High Success Rates: Many of our patients go on to successful IVF/ICSI cycles
- Compassionate Care: We understand the emotional journey and support you at every step
Frequently Asked Questions
Success rates vary, but sperm is retrieved in approximately 40–60% of NOA cases at experienced centers like Xenith IVF.
The procedure is done under anesthesia. Mild discomfort may be felt after, manageable with medications.
Costs vary by region and facility but generally range between INR 1,00,000–1,50,000. It’s best to consult directly for a detailed estimate.
Men with non-obstructive azoospermia, failed prior retrieval attempts, or genetic causes of infertility are often ideal candidates.
Yes. Since Micro-TESE often retrieves better-quality sperm, it can enhance fertilization rates during ICSI and improve overall IVF outcomes.
Micro-TESE has revolutionized the treatment of male infertility, offering renewed hope to couples struggling with azoospermia. By using microsurgical precision, this technique maximizes sperm retrieval while minimizing testicular damage.
However, its success depends heavily on the skill of the surgical team and the support of a high-quality IVF lab. If you or your partner are exploring advanced fertility options, consulting with an experienced fertility specialist is the first and most important step.
Why Choose Xenith?
We have years of experience, expertise and the latest reproductive technologies in the area of infertility and treatment plan designed for individual needs. The staff at Xenith is highly trained in the latest embryological, medical and technological know-how as well as counselling and therapeutic communication. We are equipped to offer evidence-based treatment in infertility efficiently.
- Patient-centered care
- Specialty in Recurrent IVF Failures
- Focus on interventions
- High IVF success rates
- High Clinical Standard
- All treatments under one roof
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