Advanced Sperm Retrieval for Improved Fertility Outcomes

Male infertility can be a challenging road, but modern medicine continues to bring hope through innovative techniques like Micro-TESE (Microsurgical Testicular Sperm Extraction). This advanced surgical procedure provides new hope for men facing infertility—particularly those with little to no sperm production—to achieve fatherhood.
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Introduction to Micro-TESE
Micro-TESE is a cutting-edge surgical sperm retrieval procedure used in the treatment of male infertility, especially in cases where sperm production is extremely low or absent (a condition known as non-obstructive azoospermia). Unlike standard methods, Micro-TESE uses a high-powered surgical microscope to precisely locate areas in the testes most likely to contain sperm.
Men who may benefit from Micro-TESE include:
- Those diagnosed with non-obstructive azoospermia
- Men with genetic or hormonal causes of impaired sperm production
- Patients who’ve had unsuccessful prior sperm retrieval attempts
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What Is Micro-TESE?
Micro-TESE involves the microsurgical extraction of sperm directly from the seminiferous tubules of the testicles. Using a powerful operating microscope, the surgeon identifies the most promising areas within the testes and extracts tissue in a highly targeted manner.
How It Differs from Other Methods:
- TESE (Testicular Sperm Extraction): A blind biopsy with lower precision
- TESA (Testicular Sperm Aspiration): Uses a needle to extract tissue, often with low yield
- PESA (Percutaneous Epididymal Sperm Aspiration): Used mainly for obstructive azoospermia
Micro-TESE stands out for its precision, minimal tissue damage, and higher sperm retrieval rates.
Who Needs Micro-TESE?
Micro-TESE is particularly beneficial for:
- Men with non-obstructive azoospermia (NOA): A condition where the testicles produce little or no sperm due to testicular failure
- Patients with failed previous sperm retrievals: Those who have undergone TESE or TESA with no success
- Men with genetic conditions: Such as Klinefelter syndrome or Y-chromosome microdeletions
- Cancer survivors: Especially those who’ve undergone chemotherapy or radiation therapy
A detailed evaluation by a fertility specialist can help determine if you are an ideal candidate.
Procedure: How Micro-TESE Works
Step-by-Step Overview:
- Anesthesia: The procedure is done under general anesthesia.
- Microsurgical Access: A small incision is made in the scrotum to expose the testicle.
- Microscopic Examination: Under high magnification, the surgeon examines the seminiferous tubules for areas that appear more likely to contain sperm.
- Tissue Extraction: Small pieces of tissue are removed for analysis.
- Sperm Identification: The sample is immediately examined under a microscope by embryologists to identify sperm.
- Cryopreservation: Viable sperm can be frozen for future use in IVF/ICSI procedures.
Recovery and Aftercare:
- Most men return to light activities within 2–3 days
- Mild discomfort, swelling, and bruising are common
- Full recovery typically takes 1–2 weeks
- Pain is usually well-managed with oral medication

- Higher Sperm Retrieval Rates: Especially in NOA patients compared to conventional methods
- Minimal Damage: Reduced trauma to testicular tissue due to precise targeting
- Improved IVF/ICSI Outcomes: Retrieved sperm are often of better quality
- Single Procedure Efficiency: Often eliminates the need for multiple retrievals
- Psychological Relief: Offers hope to couples who had lost faith in fertility treatment
Risks and Considerations
While Micro-TESE is generally safe, it’s important to understand potential risks:
- Swelling, bruising, or infection
- Temporary testicular discomfort or pain
- Rare complications: Hematoma or damage to blood vessels
- Underlying cause of azoospermia
- Testicular size and hormone levels
- Surgeon’s experience and technology used
- Coordination with a skilled IVF lab
ExcellentBased on 306 reviews
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Baisakhi Biswas05/06/2025Amazing experience with Xenith wakad centre.All the doctors and nurses, staffs are very good, their behaviour is so polite. Mamta ma'am and her team bring the best news of my life.Thank you all 😊Trustindex verifies that the original source of the review is Google.
Khetan Ganvir03/06/2025We are incredibly grateful to Xenith Advance Fertility Center, Wakad for making our dream come true. After a long journey, my wife conceived successfully through their expert care and guidance, and we are now expecting twins! Dr. Mamta Dighe and Dr. Pooja Chalukya were highly knowledgeable, compassionate, and supportive throughout the process. The staff made us feel comfortable and hopeful every step of the way. Their state-of-the-art facilities and personalized approach made a real difference. We couldn’t be happier with the outcome and highly recommend Xenith Advance Fertility Center to anyone struggling with infertility. Thank you for helping us start this beautiful new chapter in our lives!Trustindex verifies that the original source of the review is Google.
Nikita Badgujar30/05/2025Very Good experience, Entire team is very co-operative.Environment is also good.Trustindex verifies that the original source of the review is Google.
Shraddha Borse30/05/2025I had a truly positive experience at Xenith. From the moment I walked in, I felt comfortable and well taken care of. The Doctors & staff was friendly, efficient, and always willing to helpTrustindex verifies that the original source of the review is Google.
Neha Pohankar27/05/2025We are deeply grateful to the entire team at Xenith Center Wakad for their incredible support and care throughout our journey. From the very first visit, we felt welcomed and understood. A heartfelt thank you to the doctor for their expert guidance, to the embryologist for their dedication behind the scenes, and to the receptionists and support staff for always being kind, patient, and encouraging. Your collective compassion and professionalism made all the difference, and we will always hold a special place in our hearts for this amazing team.Trustindex verifies that the original source of the review is Google.
Yugandhara Chaudhari17/05/2025We are deeply grateful to the entire team at Xenith IVF Centre for helping us achieve our dream in the very first attempt. After going through multiple IVF failures, we began our treatment here last year — and this year, we are overjoyed to be blessed with a baby. Our heartfelt thanks to Dr. Mamata Dighe, Dr. Pooja Chalukya, and Dr. Poonam for their exceptional care, expert guidance, and personal attention throughout our journey. Their confidence, patience, and transparent communication helped calm our anxieties and brought us immense comfort. The nursing staff has been consistently kind, attentive, and compassionate at every step — always present, always supportive. We’re also thankful to the reception team, who were approachable and available even during emergencies and after hours. Our experience at Xenith has been nothing short of incredible. Thank you all for being such a vital part of this life-changing journey.Trustindex verifies that the original source of the review is Google.
nikhil16/05/2025The entire team at Xenith was very helpful and paid attention to details and patient’s need and concerns. Thanks to their constant support. Would highly recommend the facility.Trustindex verifies that the original source of the review is Google.
Shweta Dervankar15/05/2025Excellent journey......we got a positive result.....we tried a lot outside but was disappointed.....in xenith Dr. Mamta ma'am give us a hope and bring happiness in our life.....strongly recommending Xenith..... Thank you so much team...... Must visit for your infertility problem.Trustindex verifies that the original source of the review is Google.
Mayuri Darwade14/05/2025I would like to express my sincere gratitude to the entire team at Xenith IVF Centre for making our dream come true in the very first attempt. A special thanks to Dr. Mamata Dighe, Dr. Pooja Chalukya, and Dr. Poonam for their expert care, guidance, and personal attention throughout the journey. Their confidence, patience, and clear communication helped ease all our worries and gave us great comfort. The nursing staff has been extremely kind, responsive, and caring at every stage, always available, and always supportive. I’d also like to thank the reception staff, who have been readily available even during emergencies and after hours. We had a very positive and reassuring experience at Xenith. Thank you all for being such a wonderful part of this life-changing journey.Trustindex verifies that the original source of the review is Google.
J P30/04/2025We had a truly wonderful experience with Mamta Ma’am and her amazing team. From start to finish, everyone was kind, supportive, and genuinely caring. A heartfelt thank you to Pooja Ma’am, who was always just a call away whenever we had questions or needed guidance. Thanks to their expertise and constant support, we achieved a positive outcome. Highly recommended to anyone going through this journey—you’ll be in the best hands!

At Xenith IVF Center, we bring together clinical expertise, state-of-the-art technology, and a personalized approach to give you the best chance of success.
- Experienced Andrologists and Urologists: Highly skilled in microdissection techniques
- Advanced Microscopy Equipment: Allows for optimal visualization and sperm detection
- Integrated IVF Lab: Ensures seamless coordination for sperm analysis and use
- High Success Rates: Many of our patients go on to successful IVF/ICSI cycles
- Compassionate Care: We understand the emotional journey and support you at every step
Frequently Asked Questions
Success rates vary, but sperm is retrieved in approximately 40–60% of NOA cases at experienced centers like Xenith IVF.
The procedure is done under anesthesia. Mild discomfort may be felt after, manageable with medications.
Costs vary by region and facility but generally range between INR 1,00,000–1,50,000. It’s best to consult directly for a detailed estimate.
Men with non-obstructive azoospermia, failed prior retrieval attempts, or genetic causes of infertility are often ideal candidates.
Yes. Since Micro-TESE often retrieves better-quality sperm, it can enhance fertilization rates during ICSI and improve overall IVF outcomes.
Micro-TESE has revolutionized the treatment of male infertility, offering renewed hope to couples struggling with azoospermia. By using microsurgical precision, this technique maximizes sperm retrieval while minimizing testicular damage.
However, its success depends heavily on the skill of the surgical team and the support of a high-quality IVF lab. If you or your partner are exploring advanced fertility options, consulting with an experienced fertility specialist is the first and most important step.
Why Choose Xenith?
We have years of experience, expertise and the latest reproductive technologies in the area of infertility and treatment plan designed for individual needs. The staff at Xenith is highly trained in the latest embryological, medical and technological know-how as well as counselling and therapeutic communication. We are equipped to offer evidence-based treatment in infertility efficiently.
- Patient-centered care
- Specialty in Recurrent IVF Failures
- Focus on interventions
- High IVF success rates
- High Clinical Standard
- All treatments under one roof
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