Advanced Sperm Retrieval for Improved Fertility Outcomes

Male infertility can be a challenging road, but modern medicine continues to bring hope through innovative techniques like Micro-TESE (Microsurgical Testicular Sperm Extraction). This advanced surgical procedure provides new hope for men facing infertility—particularly those with little to no sperm production—to achieve fatherhood.
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Introduction to Micro-TESE
Micro-TESE is a cutting-edge surgical sperm retrieval procedure used in the treatment of male infertility, especially in cases where sperm production is extremely low or absent (a condition known as non-obstructive azoospermia). Unlike standard methods, Micro-TESE uses a high-powered surgical microscope to precisely locate areas in the testes most likely to contain sperm.
Men who may benefit from Micro-TESE include:
- Those diagnosed with non-obstructive azoospermia
- Men with genetic or hormonal causes of impaired sperm production
- Patients who’ve had unsuccessful prior sperm retrieval attempts
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What Is Micro-TESE?
Micro-TESE involves the microsurgical extraction of sperm directly from the seminiferous tubules of the testicles. Using a powerful operating microscope, the surgeon identifies the most promising areas within the testes and extracts tissue in a highly targeted manner.
How It Differs from Other Methods:
- TESE (Testicular Sperm Extraction): A blind biopsy with lower precision
- TESA (Testicular Sperm Aspiration): Uses a needle to extract tissue, often with low yield
- PESA (Percutaneous Epididymal Sperm Aspiration): Used mainly for obstructive azoospermia
Micro-TESE stands out for its precision, minimal tissue damage, and higher sperm retrieval rates.
Who Needs Micro-TESE?
Micro-TESE is particularly beneficial for:
- Men with non-obstructive azoospermia (NOA): A condition where the testicles produce little or no sperm due to testicular failure
- Patients with failed previous sperm retrievals: Those who have undergone TESE or TESA with no success
- Men with genetic conditions: Such as Klinefelter syndrome or Y-chromosome microdeletions
- Cancer survivors: Especially those who’ve undergone chemotherapy or radiation therapy
A detailed evaluation by a fertility specialist can help determine if you are an ideal candidate.
Procedure: How Micro-TESE Works
Step-by-Step Overview:
- Anesthesia: The procedure is done under general anesthesia.
- Microsurgical Access: A small incision is made in the scrotum to expose the testicle.
- Microscopic Examination: Under high magnification, the surgeon examines the seminiferous tubules for areas that appear more likely to contain sperm.
- Tissue Extraction: Small pieces of tissue are removed for analysis.
- Sperm Identification: The sample is immediately examined under a microscope by embryologists to identify sperm.
- Cryopreservation: Viable sperm can be frozen for future use in IVF/ICSI procedures.
Recovery and Aftercare:
- Most men return to light activities within 2–3 days
- Mild discomfort, swelling, and bruising are common
- Full recovery typically takes 1–2 weeks
- Pain is usually well-managed with oral medication

- Higher Sperm Retrieval Rates: Especially in NOA patients compared to conventional methods
- Minimal Damage: Reduced trauma to testicular tissue due to precise targeting
- Improved IVF/ICSI Outcomes: Retrieved sperm are often of better quality
- Single Procedure Efficiency: Often eliminates the need for multiple retrievals
- Psychological Relief: Offers hope to couples who had lost faith in fertility treatment
Risks and Considerations
While Micro-TESE is generally safe, it’s important to understand potential risks:
- Swelling, bruising, or infection
- Temporary testicular discomfort or pain
- Rare complications: Hematoma or damage to blood vessels
- Underlying cause of azoospermia
- Testicular size and hormone levels
- Surgeon’s experience and technology used
- Coordination with a skilled IVF lab
EXCELLENT Based on 335 reviews Posted on Sachin Lashkare01/11/2025Trustindex verifies that the original source of the review is Google. Dr. Pooja Mam and whole team very cooperative and supportive throughout the entire journey and made all the procedures easy and smoothly. Thank you Xenith and TeamPosted on Shambu Lala30/10/2025Trustindex verifies that the original source of the review is Google. Went through the treatment here and it was very smooth and staff was very helpful Thanks to Poonam/Pooja/Mamta ma'am for the guidancePosted on Sunita27/10/2025Trustindex verifies that the original source of the review is Google. I had very satisfied experience with xenith team.😊 The entire team gave very positive response from the beginning. Dr. Mamta mam, Dr. Pooja Mam and Dr. Pallavi Mam were very cooperative and supportive throughout the entire journey and made all the procedures easy and smoothly. Really appreciate their hard work towards their patients 😊. Also all staff members are very responsible and caring.Thank you all xenith team.❤️Posted on abhay singh26/10/2025Trustindex verifies that the original source of the review is Google. Dr. Mamta Dighe has been a pillar of strength 💪, compassion 💕, and expertise 🩺 throughout this process. She is not only exceptionally knowledgeable and up to date in her field, but also genuinely caring and considerate towards her patients. Her passion for her work and her unwavering commitment to helping couples fulfill their dreams are truly inspiring. 💖 Her guidance, professionalism, and reassuring words kept us confident throughout the process. You can clearly see how her positivity ✨ and dedication reflect in her entire team — from the embryologists 🧫 to the doctors 👩⚕️👨⚕️, nurses, and staff 👏 — everyone at Xenith is caring, helpful, and sincere. 🙌 Coming from another city for treatment was initially a big challenge, but we now feel so fortunate 🍀 to have chosen Xenith purely based on recommendations and faith in Dr. Mamta Dighe. Today, we can say it was one of the best decisions we ever made. 🌟 She has blessed us with the most precious gift anyone could ever give 👶💞, and no words can express our gratitude 🙏 for her care and support. ❤️ A very special thanks to Dr. POOJA 🌷, who has been our rock throughout this journey 🪨. Since we were away from Pune, most of our communication with Dr Pooja was over the phone 📞 — yet she never once made us feel distant. She was always there for us 🤝, patiently answering every question, addressing every worry 😌, and constantly motivating us to stay positive 🌈. Dr Pooja not only guided us medically 🩺 but also emotionally 💗, keeping our spirits high 💫 and encouraging us to stay positive. 🌈 To the entire Xenith team 👩⚕️👨⚕️💐 — thank you from the bottom of our hearts 💖. You have all played an important role in this life-changing journey 🌸. Because of your collective effort 🤲, professionalism 🏅, and compassion 💕, we are now living our dream 🌟. We wish Dr. Mamta, Dr. Pooja, Dr. Poonam and the whole Xenith family immense success 🏆 in continuing to bring joy 😊 to many more families 👨👩👧👦. May God bless you all abundantly 🙏✨ and guide you to always remain as kind 💝, dedicated 💪, and compassionate 🤍 as you are. 🌸Posted on swapnil10/10/2025Trustindex verifies that the original source of the review is Google. One of the Best IVF in Pune, Very talanted in her field. We got too good treatment form madam. I will recommend Xenith IVF to all infertility couples really looking for genuine treatmet and results.Posted on sonal jain08/10/2025Trustindex verifies that the original source of the review is Google. ⭐️⭐️⭐️⭐️⭐️ Excellent Experience at Xenith! I had a wonderful experience with the entire team at Xenith. The doctors are extremely knowledgeable, compassionate, and patient — they take the time to explain every detail and make sure you feel comfortable and confident throughout the process. The staff is equally supportive and courteous, always ready to help with a smile. From appointments to follow-ups, everything is well-organized and handled with great care. The clinic is clean, welcoming, and has a very positive atmosphere. I truly appreciate the personal attention and encouragement given at every step. Thank you to the doctors and staff at Xenith for their professionalism, warmth, and dedication — you make every patient feel valued and cared for. Highly recommended! 🌸Posted on Pratap Deshmukh05/09/2025Trustindex verifies that the original source of the review is Google. One of the best ivf centre in Pimpri chinchwad Pune.Posted on dhananjay wagh25/08/2025Trustindex verifies that the original source of the review is Google. Very very thanks to Mamta ma'am and the Xenith team specially Pooja mam and Poonam mam for giving us the biggest joy of life, our baby.

At Xenith IVF Center, we bring together clinical expertise, state-of-the-art technology, and a personalized approach to give you the best chance of success.
- Experienced Andrologists and Urologists: Highly skilled in microdissection techniques
- Advanced Microscopy Equipment: Allows for optimal visualization and sperm detection
- Integrated IVF Lab: Ensures seamless coordination for sperm analysis and use
- High Success Rates: Many of our patients go on to successful IVF/ICSI cycles
- Compassionate Care: We understand the emotional journey and support you at every step
Frequently Asked Questions
Success rates vary, but sperm is retrieved in approximately 40–60% of NOA cases at experienced centers like Xenith IVF.
The procedure is done under anesthesia. Mild discomfort may be felt after, manageable with medications.
Costs vary by region and facility but generally range between INR 1,00,000–1,50,000. It’s best to consult directly for a detailed estimate.
Men with non-obstructive azoospermia, failed prior retrieval attempts, or genetic causes of infertility are often ideal candidates.
Yes. Since Micro-TESE often retrieves better-quality sperm, it can enhance fertilization rates during ICSI and improve overall IVF outcomes.
Micro-TESE has revolutionized the treatment of male infertility, offering renewed hope to couples struggling with azoospermia. By using microsurgical precision, this technique maximizes sperm retrieval while minimizing testicular damage.
However, its success depends heavily on the skill of the surgical team and the support of a high-quality IVF lab. If you or your partner are exploring advanced fertility options, consulting with an experienced fertility specialist is the first and most important step.
Why Choose Xenith?
We have years of experience, expertise and the latest reproductive technologies in the area of infertility and treatment plan designed for individual needs. The staff at Xenith is highly trained in the latest embryological, medical and technological know-how as well as counselling and therapeutic communication. We are equipped to offer evidence-based treatment in infertility efficiently.
- Patient-centered care
- Specialty in Recurrent IVF Failures
- Focus on interventions
- High IVF success rates
- High Clinical Standard
- All treatments under one roof
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